Coffee: Good or Bad? The UltraWellness Center Moderate coffee consumption, around 14 cups per day, is consistently linked with better heart health and lower cardiovascular risk. Large meta analyses and population studies show that people who drink moderate amounts of Effects of caffeine on neuroinflammation in anxiety and depression: a systematic review of rodent studies Translational Psychiatry Is the buzz around coffee enemas boosting glutathione levelssometimes claimed to increase them by 600 700% true? The Healthiest Way to Drink Coffee