Vaping, Venous Valves, and Vein Disease Vaping Causes Immediate Effects on Vascular Function RSNA Can I Donate Blood? Common Blood Donation and Eligibility Questions Smoking (or vaping) doesn't affect your ability to donate blood. Help us bust this myth by sharing our post. We all know smoking and vaping isn't great for your health. But it doesn't stop you from being a blood or plasma donor. Just make sure to wait one hour after donating