Acetaminophen: Is Too Much of a Good Thing Too Much? Compendium of Continuing Education in Dentistry Glutathione conjugate detection (liver S9, human) US At *therapeutic* doses, what is the primary metabolic pathway for acetaminophen (paracetamol)? Phase II conjugation (glucuronidation and sulfation) Phase I oxidation by CYP3A4 Phase I oxidation by CYP2E1 Direct excretion by the PDF] Evidence that Increased Acetaminophen use in Genetically Vulnerable Children Appears to be a Major Cause of the Epidemics of Autism, Attention Deficit with Hyperactivity, and Asthma Semantic Scholar Problem 2 n acetyl para benzoquinone napqi is an oxidized