Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Adaptation to acetaminophen exposure elicits major changes in expression and distribution of the hepatic proteome Scientific Reports Can paracetamol (acetaminophen) be administered to patients with liver impairment? Hayward 2016 British Journal of Clinical Pharmacology Wiley Online Library The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism William Parker, Chi Dang Hornik, Staci Bilbo, Zoie E. Holzknecht, Lauren Gentry, Acetaminophen's Role in Autism and ADHD: A Mitochondrial Perspective