Dental Update Malignant oral melanoma: how to spot it and how it is managed Dental Update Pigmented macular lip lesion Clinical Advisor Oral melanotic macule in a leukoderma patient: a comprehensive case report Mcula melantica oral en un paciente con leucoderm Oral melanotic macule Stock Image C067 2476 Science Photo Library Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule.