Labial Macules: Dark Spots on the Lip Dermatology Advisor This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips. Lenticular melanotic macule on the lower lip of a Laugier Hunziker Download Scientific Diagram Pathology Outlines Melanotic macule Figure 9 from Pigmented lesions of the oral cavity: review, differential diagnosis, and case presentations. Semantic Scholar