Tylenol and Glutathione: A Closer Look At Their Relationship Do You Reach for Tylenol Often? Whether it's for pain, headaches, or fever Tylenol (acetaminophen) is one of the most commonly used medications. But here's something most people don't realize I'm not suggesting that there's a definitive link between Tylenol and autism, but it 100% depletes your body of glutathione, and enough studies have shown that it should only be taken when Sex differences in glutathione metabolism and acetaminophen toxicity Phases 1 and 2 acetaminophen metabolism. Acetaminophen consumed in Download Scientific Diagram