Sulfate conjugation may be the key to hepatotoxicity in paracetamol overdose Li 2021 British Journal of Clinical Pharmacology Wiley Online Library Tolerability of Paracetamol : Drug Safety Pain Basicmedical Key DRUG AND TOXIN INDUCED HEPATITIS: ACETAMINOPHEN: Acetaminophen is converted by the hepatic cytochrome P 450 drug metabolizing system to a potentially toxic metabolite that is subsequently rendered harmless through conjugation with glutathione. When
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