Toxicity of Glutathione Binding Metals: A Review of Targets and Mechanisms Glutathione Complex Martin's Wellness Feeling worse before you feel better? It might be a Herx. Also called a Jarisch Herxheimer reaction, herxing happens when Lyme microbes are killed off and release toxins into your system, sparking a Starting something like Immunocal (a glutathione precursor) can feel different for everyone., Some people report temporary differences when beginning, often described as a detox or adjustment phase Herx Reaction RyDocs