melanotic macule by joud aljuhani on Prezi Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Lip pigmentation A collection of resources for RACGP exams Next Gen GP Text Book live webinars AKT and KFP questions Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor