Give our #WednesdayWisdom practice question a try. Come back to the caption for answer rationale and references. Let's keep learning fun! . . RATIONALE Chronic alcoholics have upregulation of CYP2E1 and Glucose 6 phosphate dehydrogenase (G6PD) deficiency X linked recessive Xq28 is not true recessive as heterozygotes can express the trait; G6PD > No NADPH > No RBC glutathione protection > free radical damage hemolysis Amazon.com: We Like Vitamins NSF Certified Glutathione Supplement 500mg 60 Capsules of Reduced L Glutathione for Antioxidant & Immune Support Manufactured in USA : Health & Household Glutathione deficiency and heart failure: a systematic review of human and animal evidence ScienceDirect Amazon.com: Glutathione Supplement 1,000mg Per Serving, 98% Purity Plus Vitamin C 500mg, Active Reduced Form (GSH) Intracellular Antioxidant Supports Detoxification & Immune Health : Health & Household
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