GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. How does ethanol interfere with acetaminophen metabolism? Image: https: t.co 6EY9dIwLXY Glutathione Mediated Conjugation of Anticancer Drugs Encyclopedia MDPI Metabolite identification of ursolic acid in mouse plasma and urine after oral administration by ultra high performance liquid chromatography quadrupo RSC Advances (RSC Publishing) DOI:10.1039 C7RA11856B Critical Roles of the CysteineGlutathione Axis in the Production of Glutamyl Peptides in the Nervous System Phase II detoxification
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glucuronidation glutathione Phase II Drug Metabolism