Oral Melanotic Macule: Symptoms and Treatment Skinsight Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier Hunziker syndrome In the process of removing a Labial Melanotic Macule. A Labial Melanotic Macule is a well defined, oval, brown to black, flat patch on the central third of the lower lip, as seen Labial melanotic macule Figure 9 from Pigmented lesions of the oral cavity: review, differential diagnosis, and case presentations. Semantic Scholar