Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Acetaminophen To Use or Not to Use? SEE Alternatives, LLC Brittany Xavier here's two reasons why we don't personally use Tylenol or acetaminophen Instagram Tylenol Glutathione Kizer Wellness LLC Tylenol uses up the liver's stores of GLUTATHIONE. Glutathione is the body's most important ANTIOXIDANT.