Amide Hydrolysis Using Acid Or Base Master Organic Chemistry Reactions of Amides a) Hydrolysis Amides can break back into the acid and amine when heated with: Strong acid Strong base Example: Amide + HO Carboxylic acid + Amine b) Reduction Amides Preparation and Reactions Summary Chemistry Steps Conformational analysis and enzyme activity: models for amide hydrolysis. Henry Rzepa's Blog Henry Rzepa's Blog Carboxylic Acids and Derivatives Structure of Amides (A Level Chemistry) Study Mind