The impact of glutathione metabolism in autism spectrum disorder ScienceDirect The Interplay of Oxidative Stress, Mitochondrial Dysfunction, and Neuroinflammation in Autism Spectrum Disorder: Behavioral Implications and Therapeutic Strategies Studies show children with autism have significantly lower levels of glutathione, the body's master antioxidant. Without enough glutathione, the body struggles to eliminate toxins, making it harder to cope with everyday Studies show children with autism have significantly lower levels of glutathione, the body's master antioxidant. Without enough glutathione, the body struggles to eliminate toxins, making it harder to cope with everyday Natural Antioxidants: A Novel Therapeutic Approach to Autism Spectrum Disorders?