What is glutathione and why must we protect patient access to it? Did you know acetaminophen lowers glutathione levels? Acetaminophen, also known as Tylenol, is used to help with pain & to reduce fever. However, taking too much acetaminophen can be harmful to the liver which filters out toxins & Regarding Tylenoland Critical Thinking in Matters of Health. Apex Dental Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: