Once weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double blind, placebo controlled and active controlled, dose finding phase 2 trial The Lancet Development of Cagrilintide, a Long Acting Amylin Analogue Journal of Medicinal Chemistry What is cagrilintide (glucagon like peptide 1 receptor agonist) used for in the management of type 2 diabetes and obesity? Cagrilintide is an amylin analogue that helps regulate appetite. In a randomized trial of over 3400 patients who were overweight or obese and had 1 weight related complication, individuals assigned to a combination Presented at the ADA 85th Scientific Sessions: In the REDEFINE 2 phase 3a trial involving adults with obesity and diabetes, the use of cagrilintidesemaglutide resulted in a significantly lower body weight than