Discovery of key mechanism in Huntington's Disease could pave the way for early detection and treatment Department of Pharmacology Glutathione: The Critical Role It Plays in Multiple Sclerosis Root A Vi Glutathione Metabolism an overview ScienceDirect Topics Glutathione Pathways GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. How does ethanol interfere with acetaminophen metabolism? Image: https: t.co 6EY9dIwLXY