Frontiers Research progress of glutathione peroxidase family (GPX) in redoxidation Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic TJ. Glutathione peroxidase is an important enzyme in cellular antioxidant defense systems, detoxifying peroxides and hydroperoxides. As a component of the glutathione cycle, it protects the liver from reactive oxygen metabolites. Selenocysteine Glutathione Peroxidase 3 Deficiency Promotes Platelet Dependent Thrombosis In Vivo Circulation Glutathione peroxidase Wikipedia