Pentose Phosphate Pathway Concise Medical Knowledge Glucose metabolism begins with its transport into cells via GLUT transporters, where it is phosphorylated to glucose 6 phosphate (Glucose 6 P). This molecule can enter various pathways, including the pentose phosphate pathway or hexosamine biosynthesis. Frontiers The Role of the Pentose Phosphate Pathway in Diabetes and Cancer Pentose Phosphate Pathway Hexose Monophosphate Pathway Metabolism The Pentose Phosphate Pathway (HMP shunt) & G6PD deficiency (Favism)