Synaptogenesis: Current Biology Can gliomas provide insights into promoting synaptogenesis? Molecular Psychiatry Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Dihexa is concentrated in multiple brain regions. Rats fitted with a Download Scientific Diagram Growth factors and their peptide mimetics for treatment of traumatic brain injury ScienceDirect
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dihexa promotes synaptogenesis AngIV-Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP/PS1 Mouse via the PI3K/AKT Signaling Pathway