Labial Melanotic Macules in Atopic Dermatitis: An Observational Study Semantic Scholar Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips. Labial melanotic macule (brown spot on lip) (Stony Brook Case 1) dermatology dermatopathology Definition of melanocytic macules associated with Peutz Jeghers syndrome NCI Dictionary of Genetics Terms NCI