Pigmented Lesions of the Oral Mucosa Pocket Dentistry Labial lentigines, also called labial melanotic macules, is a benign skin condition that is more common in individuals with darker skin. They most often appear during adulthood although they can develop at Labial melanotic macule Figure 1 from Oral melanotic macule a case report. Semantic Scholar The labial melanotic macule: a review of 79 cases