Full article: Direct thrombin inhibitors and factor Xa inhibitors in patients with cerebrovascular disease New and old roles of the peripheral and brain reninangiotensinaldosterone system (RAAS): Focus on cardiovascular and neurological diseases ScienceDirect AngIV Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP PS1 Mouse via the PI3K AKT Signaling Pathway Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Dihexa Peptide: Unlocking Brain Repair, Focus, and Memory Revolution Health & Wellness