Supplements That May Aggravate SIBO SIBOINFO INB4 Peptide Papis say: Reta, GLOW, and BPC 157 all have human trials. I get it. They're not all the same. Some compounds have far better evidence than others. That's exactly the point The gut microbiome in social anxiety disorder: evidence of altered composition and function Translational Psychiatry IMO is not your typical gut imbalance. Its caused by methane producing archaea like Methanobrevibacter smithii, not bacteria making it distinct from SIBO., Unlike hydrogen based SIBO, IMO produces Potential proton pump inhibitorrelated adverse effects Perry 2020 Annals of the New York Academy of Sciences Wiley Online Library