Everyone says NAC can make glutathione. Wrong. Evidence against this is staring right at you. As you can see here, my wife's GCLC gene is genetically slower. Thus, she cannot convert Cysteine Headaches suck. There are many reasons why one gets headaches. Some reasons: Low serotonin, high histamine, low glutathione, low folate, high oxidative stress, high aldehydes, low biopterin Dehydration is a major cause Glutathione in Brain: Overview of Its Conformations, Functions, Biochemical Characteristics, Quantitation and Potential Therapeutic Role in Brain Disorders Neurochemical Research Springer Nature Link Targeting the Cysteine Redox Proteome in Parkinson's Disease: The Role of Glutathione Precursors and Beyond Glutathione with Cofactors Lozenges