Feeling worse before you feel better? It might be a Herx. Also called a Jarisch Herxheimer reaction, herxing happens when Lyme microbes are killed off and release toxins into your system, sparking a Glutathione in the Brain Encyclopedia MDPI Toxicity of Glutathione Binding Metals: A Review of Targets and Mechanisms Stop Herx Reactions 80% Success Managing Lyme Die Off Glutaredoxin catalysis requires two distinct glutathione interaction sites Nature Communications