Smoking affects the heart long before symptoms appear. Each cigarette delivers chemicals that enter the bloodstream within seconds, reaching the heart and blood vessels almost immediately. These substances damage the inner lining Two new reviews summarize how e cigs adversely affect the cardiovascular system Stanton Glantz blog Vaping Damages Blood Vessels After Just One Use, New Study Says EcoWatch Vaping just a single e cigarette can damage blood vessels, study suggests The i Paper After coronary angioplasty, quitting smoking with the help of e cigarettes reduces the risk of complications Prevention Observatory of the Montreal Heart Institute