Differential Effects of E Cigarette on Microvascular Endothelial Function, Arterial Stiffness and Oxidative Stress: A Randomized Crossover Trial Scientific Reports Smoking is a Major DVT Risk Factor: Here's What You Should Know: Kishore K. Arcot , MD, FACC, FSCAI, FSVM, RPVI: Cardiology Exposure to electronic cigarettes impairs vascular and microvascular function International Journal of Cardiology Vaping doesn't just affect your lungs it also impacts your heart and your brain. Lungs: Chemicals in vape aerosol can cause inflammation, coughing, and breathing problems. Heart: Nicotine raises Cardiovascular Disease Symptoms, Causes, Treatment & Prevention